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Purified anti-human CRP (C-reactive protein) Antib
产品名称:
Purified anti-human CRP (C-reactive protein) Antib
产品类别:
抗体
产品编号:
696006
产品应用:
696006
[价格]
规格 价格 库存
100µg ¥ 276 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human CRP/PTX1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

IHC-P - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 2.0 ?g per ml. For immunohistochemistry, a concentration range of 8?- 10??g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

For IHC-P, use 100 mM Tris, 10 mM EDTA, pH 9.0 for antigen retrieval buffer. Not recommended for use with Tris-buffered saline antigen retrieval buffer.

RRID
AB_2686984 (BioLegend Cat. No. 696006)

Antigen Details

Structure
Monomer and homopentamer
Distribution

Hepatocytes

Function
Induces expression of E-selectin and VCAM-1 expression in epithelial cells. CRP binds to target, initiates, and regulates complement activation. Induced by IL-1 and IL-6.
Interaction
Phosphocholine on the surface of apoptotic cells
Ligand/Receptor
Interacts with C1q, bacterial polysaccharide, CD64, CD32, APCS (PTX2), HDL, leptin, and fibronectin.
Biology Area
Cell Biology
Antigen References

1. Ansar W, Ghosh S. 2013. Immunol. Res. 56:131.
2. Agrawal A, et al. 2009. Adv. Exp. Med. Biol. 653:98.
3. Garlanda C, et al. 2005. Annu. Rev. Immunol. 23:337.
4. Verma S, et al. 2004. Circulation 109:1914.
5. Wadham C, et al. 2004. Circulation 109:2116.
6. Li XA, et al. 1998. Biochem. Biophys. Res. Commun. 244:249.
7. Lu J, et al. 2012. Immunol. Rev. 250:230.
8. Chen K, et al. 2006. Nat. Med. 12:425.

Gene ID
1401 View all products for this Gene ID
UniProt
View information about CRP on UniProt.org

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