Ultra-LEAF™ Purified anti-human BMP9 (GDF2)
- 产品名称：
- Ultra-LEAF™ Purified anti-human BMP9 (GDF2)
- 产品类别：
- 抗体
- 产品编号：
- 611703
- 产品应用：
- 611703
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant BMP9
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
Neut - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by neutralizing activity. The ND50 is 0.05 - 0.25 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2728466 (BioLegend Cat. No. 611703) AB_2728467 (BioLegend Cat. No. 611704)
- Structure
- Homodimer
- Distribution
-
Hepatocytes, non parenchimal cells of the liver, endothelial, stellate cells, osteosarcoma cells.
- Function
- Induces osteogenesis, chondrogenesis, differentiation of cholinergic neurons, and regulates glucose metabolism.
- Interaction
- Endothelial cells,microvascular endothelial cells, prostate cancer cells, ovarian cancer cells, osteosarcoma cells, primary myeloma cells.
- Ligand/Receptor
- Actvin receptor-like kinase- ALK-1 and ALK-5 in endothelial cells; ALK1 and BMPR-II in endothelial cells; ALK-1 and ALK-2 in mesenchymal stem cells; ALK2 and BMPR-II in myoblasts; ALK1 and endoglin in glioblastoma cells. Endoglin (CD105).
- Cell Type
- Endothelial cells
- Molecular Family
- Cytokines/Chemokines, Growth Factors
- Gene ID
- 2658 View all products for this Gene ID
- UniProt
- View information about BMP-9 on UniProt.org
