Ultra-LEAF™ Purified anti-human CXCL9 (MIG) -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 325	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human CXCL9
Formulation: 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
Preparation: The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration: The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
Application: Neut - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by neutralization of the chemotaxis induced by recombinant human CXCL9 (MIG) (Cat. No. 578106) at 0.2 ?g/mL on mouse Baf3-mCXCR3 transfectant chemoattractant cells. ND₅₀ range: 0.4 - 3 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2894528 (BioLegend Cat. No. 943503) AB_2894528 (BioLegend Cat. No. 943504)

Structure: Chemokine
Distribution: Monocytes, macrophages, antigen-presenting cells (APC), eosinophils, endothelial cells, B cells, fibroblasts in inflammatory conditions
Function: Induces chemotaxis, promotes differentiation and multiplication of leukocytes, causes tissue extravasation, enhances CNS immunity; CXCL9/CXCR3 receptor regulates immune cell migration, differentiation, and activation.
Interaction: Activated T lymphocytes, CD4 Th1, CD8+, NK, NKT cells
Ligand/Receptor: CXCR3A, CXCR3B
Cell Type: Antigen-presenting cells, B cells, Endothelial cells, Eosinophils, Fibroblasts, Macrophages, Monocytes
Biology Area: Adaptive Immunity, Angiogenesis, Cardiovascular Biology, Immuno-Oncology, Immunology, Innate Immunity, Neuroscience, Signal Transduction, Stem Cells
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Loetscher M, et al. 1996. J?Exp?Med. 184:963.
2. Lambeir AM, et al. 2001. J?Biol?Chem. 276:29839.
3. Lasagni L, et al. 2003. J?Exp?Med. 197:1537.
4. Whiting D, et al. 2004. J?Immunol. 172:7417.
5. Proost P, et al. 2004. J?Leuko?Biol. 75:777.
6. Gorbachev AV, et al. 2007. J?Immunol. 178: 2278.
7. Rosenblum JM, et al. 2010. J?Immunol. 184:3450.
8. Crawford MA, et al. 2010. PLoS Pathog. 6:e1001199.
Gene ID: 4283 View all products for this Gene ID
UniProt: View information about CXCL9 on UniProt.org