Purified anti-human IL-32α Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 265	1

规格

价格

库存

100µg

￥ 265

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human IL-32α
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Clone A15159A?does not cross-react with mouse (in-house tested).
RRID: AB_2650733 (BioLegend Cat. No. 694702)

Structure: 131 amino acids with a predicted molecular weight of 15 kD.
Distribution: Secreted by T cells, natural killer cells, dendritic cells, and keratinocytes.
Function: IL-32α expression can be induced by IL-18, IL-1β, IFN-γ, IL-12 and IL-17. The activity of IL-32α can be significantly increased by limited cleavage of IL-32α by neutrophil proteinase 3.
Interaction: IL-32α has been reported to interact with neutrophil proteinase 3, PKC, STAT3, integrin and paxilin.
Cell Type: T cells, NK cells, Dendritic cells
Biology Area: Cell Biology, Immunology
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Joosten LA, et al. 2013. Cell. Mol. Life Sci. 70:3883.
2. Kang JW, et al. 2012.?J. Biol. Chem. 287:35556.
3. Cheon S, et al. 2011. J. Biol. Chem. 286:12049.
4. Nishida A,?et al. 2009. J. Biol. Chem. 284:17868.
5. Heinhuis B, et al. 2012. J. Biol. Chem. 287:5733.
6. Novick D, et al. 2006. Proc. Natl. Acad. Sci. USA 103:3316.
7. Shioya M, et al. 2007. Clin. Exp. Immunol. 149:480.?
Gene ID: 9235 View all products for this Gene ID
UniProt: View information about IL-32alpha on UniProt.org