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APC anti-human CD130 (gp130) Antibody
产品名称:
APC anti-human CD130 (gp130) Antibody
产品类别:
抗体
产品编号:
362006
产品应用:
362006
[价格]
规格 价格 库存
100tests ¥ 338 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
GP130 (23-619aa) recombinant protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Product Citations
  1. Silvin A, et al. 2020. Cell. 182:1401. PubMed
  2. Baryawno N et al. 2019. Cell. 177(7):1915-1932 . PubMed
  3. Saga R, et al. 2019. Oncol Lett. 17:3555. PubMed
  4. Wilmes S, et al. 2021. Elife. 10:. PubMed
  5. Hara T, et al. 2021. Cancer Cell. 39(6):779-792.e11. PubMed
RRID
AB_2563403 (BioLegend Cat. No. 362005) AB_2563404 (BioLegend Cat. No. 362006)

Antigen Details

Structure
130 kD type I transmembrane glycoprotein.
Distribution

T cells, activated B cells, monocytes, plasma cells, endothelial cells and epithelial cells.

Function
Common β subunit of IL-6 receptor family, plays a role in signal transduction.
Ligand/Receptor
IL-6, IL-11, OSM, CNTF, CT-1, NP, IL-27.
Cell Type
B cells, Endothelial cells, Epithelial cells, Monocytes, Plasma cells, T cells
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Arzt E, et al. 2001. J. Clin. Invest. 108:1729.
2. Bravo J, et al. 2000. EMBO J. 19:2399.
3. Wang XJ, et al. 1998. Blood 91:3308.
4. Hibi. M, et al. 1990. Cell. 63:1149.
5. Schlossman S, et al.?1995. ed. Leukocyte Typing V. New York. Oxford University Press.

Gene ID
3572 View all products for this Gene ID
UniProt
View information about CD130 on UniProt.org

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