Ultra-LEAF™ Purified anti-human IL-3 Antibod-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 270	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human IL-3
Formulation: 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.
Preparation: The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration: The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
Application: Neut - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by neutralizing activity. The ND₅₀ is 0.3 – 1.5 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2650727 (BioLegend Cat. No. 694303) AB_2650728 (BioLegend Cat. No. 694304)

Structure: Cytokine
Distribution: Activated T cells, Th1, Th2, mast cells, eosinophils, keratinocytes, NK cells, and endothelial cells.
Function: IL-3 is a pleiotropic factor which promotes both self-renewal and differentiation of early multipotential progenitors and is involved in inducible hematopoiesis in response to infections.
Interaction: Erythroid cells, megakaryocytes, neutrophils, eosinophils, basophils, mast cells, monocytic lineages.
Ligand/Receptor: Heterodimer IL-3Rα (CD123) and a common β subunit (βc) that is shared with the IL-5R and GM-CSFR.
Cell Type: Endothelial cells, Eosinophils, Mast cells, NK cells, T cells, Th1, Th2
Biology Area: Cell Biology
Molecular Family: Cytokines/Chemokines
Antigen References: 1.?Kitamura T, et al. 1989. J. Cell. Physiol. 140:323.
2. Kohno M, et al. 2005. Blood 105:2059.
3. Murphy JM, Young IG. 2006. Vitam. Horm. 74:1.
4. Kleemann R, et al. 2008. Cardiovasc. Res. 79:360.
5. Valent P, and Dahinden CA. 2010. Curr. Opin. Hematol. 17:60.
6. Mirza S, et al. 2010. J. Biol. Chem. 285:22370.
Gene ID: 3562 View all products for this Gene ID
UniProt: View information about IL-3 on UniProt.org