Ultra-LEAF™ Purified anti-human IL-11 Antibo-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 270	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human IL-11.
Formulation: Phosphate-buffered solution, pH 7.2.
Preparation: The antibody was purified by affinity chromatography.
Concentration: The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: Neut - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by neutralizing activity. The ND₅₀ is 0.2 – 0.8 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2650725 (BioLegend Cat. No. 694203) AB_2650726 (BioLegend Cat. No. 694204)

Structure: Cytokine
Distribution: Epithelial, endothelial, keratinocytes, stromal, neuronal, fibroblasts, osteoclasts, and bone marrow stromal cells.
Function: IL-11 plays important roles in hemopoiesis, thrombopoiesis, megakaryocytopoiesis, and bone resorption; It regulates macrophage differentiation and confers mucosal protection after chemotherapy and radiation therapy.
Interaction: Hematopoietic cells, hepatocytes, adipocytes, neurons, osteoblasts, fibroblasts, and gastrointestinal epithelial cells.
Ligand/Receptor: Membrane bound or soluble IL-11Rα heterodimerize with gp130β.
Cell Type: Endothelial cells, Epithelial cells, Fibroblasts, Osteoclasts
Biology Area: Cell Biology
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Putoczki T and Ernst M. 2010. J. Leuko. Biol. 88 1109.
2. Wilde MI and Faulds D. 1998. BioDrugs 10:159.
3. Barton VA, et al. 2000. J. Biol. Chem. 275:36197.
4. Robb L, et al. 1998. Nat. Med. 4:303.
5. Lemoli RM, et al. 1995. Br. J. Haematol. 91:319.
6. Elias JA, et al. 1994. J. Biol. Chem. 269:22261.
7. Chen Q, et al. 2005. J. Immunol. 174:2305.
Gene ID: 3589 View all products for this Gene ID
UniProt: View information about IL-11 on UniProt.org