Ultra-LEAF™ Purified anti-human S100A8/A9 He-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 270	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human A100A8/A9
Formulation: 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.
Preparation: The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration: The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
Application: Block -?Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by blocking activity. The ND50 is 2 - 8 ?g/mL. ?It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2687183 (BioLegend Cat. No. 697503) AB_2687184 (BioLegend Cat. No. 697504)

Structure: Non-covalent heterodimer.
Distribution: Neutrophils, monocytes, macrophages, gingival keratinocytes, granulocytes, osteoclasts, fibroblasts, and microvascular endothelial cells.
Function: Pro-inflammatory molecule that possesses antimicrobial properties. Is up-regulated in neutrophils and monocytes at the sites of inflammation.
Interaction: Astrocytes, neutrophils, and monocytes.
Ligand/Receptor: RAGE, TLR4
Cell Type: Neutrophils, Monocytes, Macrophages, Granulocytes, Osteoclasts, Fibroblasts, Endothelial cells
Biology Area: Cell Biology, Neuroscience, Stem Cells, Synaptic Biology
Molecular Family: Growth Factors, Cytokines/Chemokines
Antigen References: 1. Sampson B,?et al.?2002.?Lancet.?360:1742-5.
2. Vogl T,?et al. 2007.?Nat. Med.?13:1042-9.
3. Semprini S,?et al.?2002.?Hum. Genet.?111:310-3.
4. Corbin BD,?et al.?2008.?Science?319:962-5.
5. Gopal R,?et al. 2013.?Am. J. Respir. Crit. Care Med.?188:1137-46.
6. Siegenthaler G,?et al.?1997.?J. Biol. Chem.?14:9371-7.
7. Ryckman C,?et al.?2003.?J. Immunol.?170:3233-42.
8. Ryu MJ,?et al.?2012.?J. Biol. Chem.?287:22948-58.
9. Ehrchen JM,?et al.?2009.?J. Leuko. Biol.?3:557-66.
10. Wang J,?et al.?2015.?FASEB J.?29(1):250-62.
11. Champaiboon C,?et al.?2009.?J. Biol. Chem.?284:7078.
Gene ID: 6279 View all products for this Gene ID
UniProt: View information about S100A8/A9 Heterodimer on UniProt.org