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Purified anti-human Galectin-4 Antibody
产品名称:
Purified anti-human Galectin-4 Antibody
产品类别:
抗体
产品编号:
397002
产品应用:
397002
[价格]
规格 价格 库存
100µg ¥ 382 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human Galectin-4
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2810609 (BioLegend Cat. No. 397002)

Antigen Details

Structure
Contains at least two distinct carbohydrate recognising domains (CRD).
Distribution

It is expressed in oral mucosa, esophagus, gastrointestinal epithelium, and intestinal epithelial cell lines.

Function
Controls intestinal inflammation, intestinal epithelial wound healing, protein apical trafficking, and stabilizes adherens junctions and lipid rafts in the microvillus membrane.
Interaction
T cells and macrophages.
Ligand/Receptor
Galectin-4 binds to glycosphingolipids with 3-O-sulfated Gal residues and carcinoembryonic antigens.
Cell Type
Epithelial cells
Biology Area
Cancer Biomarkers, Immunology
Antigen References

1. Rabinovich GA,?et al.?2002.?J Leuko Biol.?71:741.
2. Huflejt ME, Leffler H. 2004.?Glycoconj J.?20:247.
3. Ideo H,?et al.?2005.?J Biol Chem.?6:4730-7.
4. Markova V,?et al.?2006.?Int J Mol Med.?18:65.
5. Paclik D,?et al.?2008.?Inflamm Bowel Dis.?14:1366.
6. Paclik D,?et al.?2008.?PLoS One?3(7):e2629.
7. Belo A,?et al.?2013.?PLoS One?8(6):e65957.
8. Houzelstein D,?et al.?2013.?J Histochem Cytochem.?61:348.
9. Viguier M,?et al.?2014.?Tissue Barriers?2:e29103.
10. Cai Z,?et al.?2014.?Cancer Sci.?105:1510.

Gene ID
3960 View all products for this Gene ID
UniProt
View information about Galectin-4 on UniProt.org

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