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Alexa Fluor® 594 anti-human Galectin-4 Antibod
产品名称:
Alexa Fluor® 594 anti-human Galectin-4 Antibod
产品类别:
抗体
产品编号:
397003
产品应用:
397003
[价格]
规格 价格 库存
25µg ¥ 159 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human Galectin-4
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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RRID
AB_2814368 (BioLegend Cat. No. 397003) AB_2814369 (BioLegend Cat. No. 397004)

Antigen Details

Structure
Contains at least two distinct carbohydrate recognising domains (CRD).
Distribution

It is expressed in oral mucosa, esophagus, gastrointestinal epithelium, and intestinal epithelial cell lines.

Function
Controls intestinal inflammation, intestinal epithelial wound healing, protein apical trafficking, and stabilizes adherens junctions and lipid rafts in the microvillus membrane.
Interaction
T cells and macrophages.
Ligand/Receptor
Galectin-4 binds to glycosphingolipids with 3-O-sulfated Gal residues and carcinoembryonic antigens.
Cell Type
Epithelial cells
Biology Area
Cancer Biomarkers, Immunology
Antigen References

1. Rabinovich GA,?et al.?2002.?J Leuko Biol.?71:741.
2. Huflejt ME, Leffler H. 2004.?Glycoconj J.?20:247.
3. Ideo H,?et al.?2005.?J Biol Chem.?6:4730-7.
4. Markova V,?et al.?2006.?Int J Mol Med.?18:65.
5. Paclik D,?et al.?2008.?Inflamm Bowel Dis.?14:1366.
6. Paclik D,?et al.?2008.?PLoS One?3(7):e2629.
7. Belo A,?et al.?2013.?PLoS One?8(6):e65957.
8. Houzelstein D,?et al.?2013.?J Histochem Cytochem.?61:348.
9. Viguier M,?et al.?2014.?Tissue Barriers?2:e29103.
10. Cai Z,?et al.?2014.?Cancer Sci.?105:1510.

Gene ID
3960 View all products for this Gene ID
UniProt
View information about Galectin-4 on UniProt.org

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