HRP anti-Tau Phospho (Ser262) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 153	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Tau Phospho (Ser262) peptide conjugated to KLH.
Purity: The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Formulation: This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Concentration: 0.5 mg/ml
Storage & Handling: Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application: IHC-P - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2728571 (BioLegend Cat. No. 849503) AB_2728572 (BioLegend Cat. No. 849504)

Structure: Unmodified Tau isoforms have an apparent molecular weight ranging from 33-79 kD. Additional high and low molecular weight Tau species have been observed in brain tissues.
Distribution: Tissue distribution: Central nervous system, peripheral ganglia and nerves, kidney, skeletal, and heart muscle.
Cellular distribution: Cytoskeleton, nucleus, plasma membrane, and cytosol.
Function: Tau promotes microtubule assembly and stability. The short tau isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Interaction: Tau interacts with Sequestosome-1, Peptidyl-prolyl cis-trans isomerase FKBP4, Casein kinase I isoform delta, Serine/threonine-protein kinase Sgk1, Laforin, Alpha-synuclein
Biology Area: Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family: Phospho-Proteins
Antigen References: 1. Augustinack JC, et al. 2002. Acta Neuropath. 103(1):26-35. PubMed.
2. Seubert P, et al. 1995. J Biol Chem 270(32):18917-22. PubMed.
3.?Dong Y, et al. 2012. PLoS One 7(6):e39386. PubMed.
Gene ID: 4137 View all products for this Gene ID
UniProt: View information about Tau Phospho Ser262 on UniProt.org