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Purified anti-human BDNF Antibody
产品名称:
Purified anti-human BDNF Antibody
产品类别:
抗体
产品编号:
536702
产品应用:
536702
[价格]
规格 价格 库存
500µg ¥ 581 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ELISA Capture - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. For ELISA Capture applications, a concentration range of 1 - 4 ?g/mL is recommended. To obtain a linear standard curve, serial dilutions of BDNF recombinant protein ranging from 156.3 to 10,000 pg/mL is recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The purified A15062G antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated A15062F antibody (Cat. No. 536804) as the detection antibody and Recombinant Human BDNF (ELISA Std.) (Cat. No. 759709).

Although not tested, additional species reactivity for rat, donkey, equine, porcine, and monkey are predicted based on 100% amino acid sequence conservation for this target across listed species.

RRID
AB_2783342 (BioLegend Cat. No. 536702)

Antigen Details

Structure
Noncovalently linked homodimer.
Distribution

Ubiquitous with high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung, and testis.

Function
Supports the survival of sensory and sympathetic neurons, and also dopaminergic midbrain neurons.
Interaction
Sensory neurons, sympathetic neurons, midbrain dopaminergic neurons
Ligand/Receptor
TrkB
Antigen References
  1. Baloh RH,?et al.?1998.?Neuron.?21:1291.
  2. Masure S,?et al.?1999.?Eur. J. Biochem.?266:892-902.
  3. Gardell LR,?et al.?2003.?Nat. Med.?9(11):1383-9.
  4. Honma Y,?et al.?2002.?Neuron.?35:267-82.
  5. Banerjee A,?et al.?2012.?PLoS One?7(11):e50098.
  6. Wong LE,?et al.?2015.?Proc. Natl. Acad. Sci. USA?112:6170-5.
  7. Zhang M,?et al.?2016.?Oncotarget.?7:3267-82.
Gene ID
627 View all products for this Gene ID
UniProt
View information about BDNF on UniProt.org

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