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首页 > 抗体蛋白 > 抗体
Purified anti-HGF Antibody
产品名称：
Purified anti-HGF Antibody
产品类别：
抗体
产品编号：
692602
产品应用：
692602
[价格]
规格 价格 库存
100µg ￥ 253 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant Human HGF (carrier-free)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per mL. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody works for Western blotting under non-reducing conditions only and does not cross-react with mouse.

RRID
AB_2632766 (BioLegend Cat. No. 692602)

Antigen Details

Structure
Heterodimer (alpha and beta chains). Pro-HGF has 728 amino acids, the predicted molecular weight is approximately 83 kD. The alpha and beta chains contain 463 and 234 amino acids and have a predicted molecular mass of approximately 53.6 and 26 kD respec
Distribution

Mesenchymal cells, liver sinusoidal endothelial, and macrophages.

Function
Stimulates epithelial cell proliferation, motility, morphogenesis and angiogenesis. Hypoxia and hyperglycemia suppress HGF production. Also, TGF-β and angiotensin-II depress HGF production in vitro.
Interaction
Hepathocytes and epithelial cells.
Ligand/Receptor
MET receptor.
Biology Area
Angiogenesis, Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Biology, Cell Proliferation and Viability, Immunology, Signal Transduction
Molecular Family
Cytokines/Chemokines, Growth Factors
Antigen References

1. Hartmann S, et al. 2016. Clin. Cancer Res. 22:4005.
2. Fajardo-Puerta AB, et al. 2016. J. Clin. Pathol. 69:575.
3. Zhang Y, et al. 2016. Oncotarget. 7:37370-89.
4. Frisch RN, et al. 2016. Expert Opin. Ther. Targets 20:1087.
5. Kataoka H, et al. 2000. J. Biol. Chem. 275:40453.
6. Wang X, et al. 2002. Mol. Cell. 9:411.
7. Wu MH, et al. 2004. Gene Ther. 11:170.
8. Mizuno S, et al. 2008. Front. Biosci. 13:7072.
9. D'Angelo F, et al. 2013. Clin. Exp. Immunol. 174:60.

Gene ID
3082 View all products for this Gene ID
UniProt
View information about HGF on UniProt.org

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