Purified anti-NTRK2 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 276	1

规格

价格

库存

100µg

￥ 276

Product Details

Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Purified recombinant full length of human NTRK2
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB -?Quality tested
Recommended Usage: Optimal concentration of usage is 0.1 - 1 ?g/mL for WB. The optimal concentration should be determined by titration for each individual assay of interest
RRID: AB_2686965 (BioLegend Cat. No. 695102)

Structure: Human NTRK2 has 7 isoforms, and predicted Mw ranges from 35 to 93kDa. It has 11 potential N-glycosylation sites.
Distribution: NTRK2 is found primarily in the nervous system. It also can be found in the pancreas, skeletal muscles, and the kidney. A truncated form of TrkB (missing the tyrosine kinase domain) is found in heart, ovary, and the spleen.
Function: NTRK2, when binded to BDNF, NT-3, and NT-4, is able to exert neuron cells' biological functions such as proliferation, survival, axon, and dendrite growth.
Interaction: Interacts with SHC1, PLCG1 and/or PLCG2, SH2B1 and SH2B2, NGFR, SH2D1A, SQSTM1 and KIDINS220, FRS2.
Ligand/Receptor: BDNF, NT-3 and NT-4.
Biology Area: Cell Biology, Neuroscience, Synaptic Biology
Molecular Family: Soluble Receptors, Protein Kinases/Phosphatase
Antigen References: 1.?Snider WD. 1994.?Cell?77:627.
2. Grace PM,?et al.?2014.?Nat. Rev. Immunol.?14:217.
3.?Neveu I and Arenas E. 1996.?J. Cell Biol.?133:631.
4.?Green CR,?et al.?2013.?J. Depress Anxiety?S4:006.
5.?Gupta VK,?et al.?2013.?Int. J. Mol. Sci.?14:10122.
6.?Pla P,?et al.?2014.?Front Behav. Neurosci.?8:135.
7.?Liu X,?et al.?2014.?J. Biol. Chem.?289:27571.
Gene ID: 4915 View all products for this Gene ID
UniProt: View information about NTRK2 on UniProt.org