Purified anti-human CD127 (IL-7Rα) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 124	1

Product Details

Verified Reactivity

Human

Reported Reactivity

African Green, Baboon, Cynomolgus, Rhesus

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Recombinant human CD127

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
PG - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported (for the relevant formats) application: proteogenomics¹.

Application References (PubMed link indicates BioLegend citation)

Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)

Product Citations

Rouers A, et al. 2021. Cell Rep Med. 2:100278. PubMed
Fu J et al. 2019. Cell stem cell. 24(2):227-239 . PubMed
Abdel-Gadir A, et al. 2019. Nat Med. 25:1164. PubMed
Mousset CM, et al. 2018. Oncoimmunology. 7:e1488565. PubMed
Alroqi F, et al. 2017. J Clin Immunol. . 10.1007/s10875-017-0451-1. PubMed
Kaufmann M, et al. 2021. Med. 2(3):296-312.e8. PubMed
Kondo H, et al. 2022. Front Immunol. 13:836923. PubMed
Fan J, et al. 2019. Nat Commun. 1.984027778. PubMed
Oba T, et al. 2021. J Immunother Cancer. 9:. PubMed
Li Y, et al. 2019. Front Immunol. 0.460416667. PubMed
Yoshihara S, et al. 2019. Front Immunol. 0.545833333. PubMed
Cobb DA, et al. 2022. J Immunother Cancer. 10:. PubMed
Martin JC, et al. 2020. Cell. 178(6):1493-1508.e20.. PubMed
Michlmayr D, et al. 2020. Cell Reports. 31(4):107569. PubMed
Tripathi T, et al. 2019. Immunohorizons. 0.201388889. PubMed
Lundtoft C, et al. 2017. PLoS Pathogens. 13(6):e1006425. PubMed
Chng MHY, et al. 2020. Immunity. 51(6):1119-1135.e5.. PubMed
Cardoso V, et al. 2017. Nature. 549:277. PubMed
NULL, et al. 2022. Cell. 185:916. PubMed
Mishra A, et al. 2021. Cell. 184(13):3394-3409.e20. PubMed
Schwabenland M, et al. 2021. Immunity. . PubMed
Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
Umeda M, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
Lavin Y et al. 2017. Cell. 169(4):750-765 . PubMed

RRID

AB_10718513 (BioLegend Cat. No. 351302)

Antigen Details

Structure: Type I transmembrane glycoprotein, associates with CD132, 60-90 kD
Distribution: Immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, bone marrow stromal cells
Function: T cell and immature B cell proliferation and development
Ligand/Receptor: IL-7
Cell Type: B cells, T cells, Thymocytes, Tregs
Biology Area: Immunology
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors
Antigen References: 1. Sudo T, et al. 1993. P. Natl. Acad. Sci. USA 90:9125.
2. He YW and Malek TR. 1998. Crit. Rev. Immunol. 18:503.
3. Huster KM, et al. 2004. P. Natl. Acad. Sci. USA 101:5610.
4. Pillai M, et al. 2004. Leukemia Lymphoma 45:2403.
5. Morrissey PJ, et al. 1989. J. Exp. Med. 169:707.
6. Liu W, et al. 2006. J. Exp. Med. 203:1701.
Gene ID: 3575 View all products for this Gene ID
UniProt: View information about CD127 on UniProt.org

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