PerCP/Cyanine5.5 anti-human CD127 (IL-7Rα) A-上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 188	1

Product Details

Verified Reactivity

Human

Reported Reactivity

African Green, Baboon, Cynomolgus, Rhesus

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Recombinant human CD127

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Application Notes

Additional reported (for the relevant formats) application: proteogenomics¹.

Additional Product Notes

View more applications data for this product in our Scientific Poster Library.

BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.

Application References (PubMed link indicates BioLegend citation)

Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)

Product Citations

Schmidleithner L et al. 2019. Immunity. 50(5):1232-1248 . PubMed
Palamides P, et al. 2016. Dis Model Mech. 9: 985 - 997. PubMed
Ramien C, et al. 2020. Cell Reports. 29(4):810-815. PubMed
Roukens AHE, et al. 2022. Nat Immunol. 23:23. PubMed
Pan YG, et al. 2021. Immunity. 54(6):1245-1256.e5. PubMed
Wu J, et al. 2021. Front Immunol. 12:601611. PubMed
Shevyrev D, et al. 2021. Exp Ther Med. 209:21. PubMed
Goodwin M, et al. 2020. Sci Adv. 6:eaaz0571. PubMed
Chen Y, et al. 2021. Transl Lung Cancer Res. 10:2193. PubMed
Fujigaki J, et al. 2015. PLoS One. 10: 0132521. PubMed
Shen C, et al. 2021. Front Immunol. 12:680055. PubMed
Van Zeebroeck L, et al. 2021. Front Immunol. 12:655122. PubMed
OConnor RA, et al. 2021. OncoImmunology. 10(1):1940675. PubMed
Santoni de Sio FR, et al. 2018. J Allergy Clin Immunol. 142:1909. PubMed
Hui Z, et al. 2022. Cell Death Dis. 13:607. PubMed

RRID

AB_10900253 (BioLegend Cat. No. 351321) AB_10897104 (BioLegend Cat. No. 351322)

Antigen Details

Structure: Type I transmembrane glycoprotein, associates with CD132, 60-90 kD
Distribution: Immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, bone marrow stromal cells
Function: T cell and immature B cell proliferation and development
Ligand/Receptor: IL-7
Cell Type: B cells, T cells, Thymocytes, Tregs
Biology Area: Immunology
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors
Antigen References: 1. Sudo T, et al. 1993. P. Natl. Acad. Sci. USA 90:9125.
2. He YW and Malek TR. 1998. Crit. Rev. Immunol. 18:503.
3. Huster KM, et al. 2004. P. Natl. Acad. Sci. USA 101:5610.
4. Pillai M, et al. 2004. Leukemia Lymphoma 45:2403.
5. Morrissey PJ, et al. 1989. J. Exp. Med. 169:707.
6. Liu W, et al. 2006. J. Exp. Med. 203:1701.
Gene ID: 3575 View all products for this Gene ID
UniProt: View information about CD127 on UniProt.org

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