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PE/Cyanine7 anti-human CD127 (IL-7Rα) Antibo
产品名称：
PE/Cyanine7 anti-human CD127 (IL-7Rα) Antibo
产品类别：
抗体
产品编号：
351319
产品应用：
351319
[价格]
规格 价格 库存
25tests ￥ 176 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human CD127
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported (for the relevant formats) application: proteogenomics1.

Additional Product Notes
BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
Product Citations
  1. Yang M, et al. 2019. Cell Physiol Biochem. 52:1178. PubMed
  2. Turner JA, et al. 2020. Immunity. 53:1202. PubMed
  3. Kim CJ, et al. 2018. Immunity. 49:1034. PubMed
  4. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  5. Mashiko S, et al. 2015. J Allergy Clin Immunol. 136: 351-359. PubMed
  6. Catapano M, et al. 2020. J Invest Dermatol. 140:816. PubMed
  7. Withers D, et al. 2016. Nat Med. 22:319-23. PubMed
  8. Nicholas DA et al. 2019. Cell Metab. 30(3):447-461 . PubMed
  9. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  10. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  11. Hardman CS, et al. 2021. Sci Immunol. 6:. PubMed
  12. Idorn M, et al. 2018. Oncoimmunology. 7:e1412029. PubMed
  13. Shafiei-Jahani P, et al. 2021. Nat Commun. 12:2526. PubMed
  14. Lundtoft C, et al. 2017. PLoS Pathogens. 13(6):e1006425. PubMed
  15. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  16. Knoop J, et al. 2020. Diabetes. 661:69. PubMed
  17. Waddington KE, et al. 2020. Front Immunol. 1.51875. PubMed
  18. Saraiva DP, et al. 2018. Front Immunol. 2.184027778. PubMed
  19. Reuschl AK, et al. 2022. Cell Rep. 39:110650. PubMed
  20. Serr I, et al. 2016. Nat Commun. 7:10991. PubMed
  21. Goc J, et al. 2021. Cell. :. PubMed
  22. Nasrallah R, et al. 2020. Nature. 583:447. PubMed
RRID
AB_10899414 (BioLegend Cat. No. 351319) AB_10897098 (BioLegend Cat. No. 351320)

Antigen Details

Structure
Type I transmembrane glycoprotein, associates with CD132, 60-90 kD
Distribution

Immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, bone marrow stromal cells

Function
T cell and immature B cell proliferation and development
Ligand/Receptor
IL-7
Cell Type
B cells, T cells, Thymocytes, Tregs
Biology Area
Immunology
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References

1. Sudo T, et al. 1993. P. Natl. Acad. Sci. USA 90:9125.
2. He YW and Malek TR. 1998. Crit. Rev. Immunol. 18:503.
3. Huster KM, et al. 2004. P. Natl. Acad. Sci. USA 101:5610.
4. Pillai M, et al. 2004. Leukemia Lymphoma 45:2403.
5. Morrissey PJ, et al. 1989. J. Exp. Med. 169:707.
6. Liu W, et al. 2006. J. Exp. Med. 203:1701.

Gene ID
3575 View all products for this Gene ID
UniProt
View information about CD127 on UniProt.org

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