Purified anti-DDX58 (RIG-I) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 288	1

规格

价格

库存

100µg

￥ 288

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial DDX58 recombinant protein (1-228 a.a.) expressed in E. coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2564246 (BioLegend Cat. No. 662302)

Structure: 925 amino acids with a predicted molecular weight of 107 kD. Contains two CARD domains, one RNA helicase domain and one CTD domain.
Distribution: Cytoplasm
Function: DDX58 is a RNA helicase participating in the innate immune responses during viral infection. It acts as a cytoplasmic sensor of viral RNA and activates the production of proinflammatory cytokines and type I interferons.
Interaction: DDX58 forms homodimers upon binding to viral double stranded (ds) RNA. Interacts with TMEM173, DHX58, TRIM25, NLRC5, and MAVS.
Biology Area: Cell Biology, Immunology, Innate Immunity, Signal Transduction
Antigen References: 1. Goubau D, et al. 2013. Immunity. 38:855.
2. Zhang HX, et al. 2013. Proc. Natl. Acad. Sci. USA. 110:6459.
3. Wang Y, et al. 2013. Innate Immun. 19:193.
4. Oshiumi H, et al. 2012. J. Biochem. 151:5.
5. Kolakofsky D, et al. 2012. RNA. 18:2118.
6. Schlee M, et al. 2010. Mol. Ther. 18:1254.
Gene ID: 23586 View all products for this Gene ID
UniProt: View information about DDX58 on UniProt.org