Purified anti-TRAF3 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 229	1

规格

价格

库存

100µg

￥ 229

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial TRAF3 recombinant protein (1-200 a.a.) expressed in E. coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
KO/KD-WB - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2566432 (BioLegend Cat. No. 680802)

Structure: 568 amino acids with a predicted molecular weight of 64.5 kD. Contains a C-terminal MATH/TRAF domain responsible for the binding to receptor cytoplasmic domains.
Distribution: Cytoplasm.
Function: TRAF3 mediates the signal transduction from TNF receptors and Toll-like receptors, leading to the activation of NF-κB, MAP kinases, or IRF3. TRAF3 is involved in the regulation of anti-viral response and B-cell survival.
Interaction: TRAF3 forms a homodimer. TRAF3 also forms heterodimers with TRAF2 and TRAF5. TRAF3 also interacts with CD40, TICAM1, TRAFD1, BIRC2, BIRC3, TLR4. TRIP, and TBK1.
Biology Area: Cell Biology, Immunology, Innate Immunity, Signal Transduction
Antigen References: 1. Hildebrand JM, et al. 2011. Immunol. Rev. 244:55.
2. Hu H, et al. 2013. Nature 494:371.
3. Jenkinson SR, et al. 2013. Proc. Natl. Acad. Sci. USA 110:21107.
4. Lin WW, et al. 2013. Front Immunol. 4:477.
5. Yi Z, et al. 2014. Cytokine Growth Factor Rev. 25:147.
6. Yi Z, et al. 2014. Nat. Immunol. 15:866.
Gene ID: 7187 View all products for this Gene ID
UniProt: View information about TRAF3 on UniProt.org