PE anti-BATF Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 153	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Full length human BATF recombinant protein.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Product Citations

RRID

AB_2563516 (BioLegend Cat. No. 654803) AB_2563517 (BioLegend Cat. No. 654804)

Structure: 14 kD protein containing a bZIP (basic-leucine zipper) domain, which mediates dimerization with Jun family members.
Distribution: Nucleus. Expressed most abundantly in hematopoietic tissues.
Function: AP-1 transcription complexes regulate gene expression in response to various stimuli, such as cytokines, growth factors, stress, and infection. BATF belongs to the AP-1/ATF superfamily and negatively regulates AP-1 mediated transcription when it forms heterodimers with Jun proteins.
Interaction: Forms heterodimers with c-Jun, JunB, and JunD. Interacts with IFI35, IRF4, and IRF8 through bZIP domain.
Cell Type: B cells, Dendritic cells
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Transcription Factors
Molecular Family: Nuclear Markers
Antigen References: 1. Betz BC, et al. 2010. J. Exp. Med. 207:933.
2. Dorsey MJ, et al. 1995. Oncogene 11:2255.
3. Echlin DR, et al. 2000. Oncogene 19:1752.
4. Johansen LM, et al. 2003. J. Virol. 77:6029.
5. Schraml BU, et al. 2009. Nature 460:405.
6. Tussiwand R, et al. 2012. Nature 490:502.
Gene ID: 10538 View all products for this Gene ID
UniProt: View information about BATF on UniProt.org