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Purified anti-NLRP2 Antibody
产品名称:
Purified anti-NLRP2 Antibody
产品类别:
抗体
产品编号:
673902
产品应用:
673902
[价格]
规格 价格 库存
100µg ¥ 265 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial NLRP2 recombinant protein (60-192 aa) expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
Upon receipt, store undiluted at 4°C
Application

WB - Quality tested
ICC?- Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per mL. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2564486 (BioLegend Cat. No. 673902)

Antigen Details

Structure
1062 amino acids with a predicted molecular weight of 120.5 kD; contains a DAPIN domain, NACT domain, and eight LRR repeats.
Distribution

Cytoplasm

Function
NLRP2 is a component of inflammasome that is involved in the activation of caspase-1 and the inhibition of NK&κB signaling.
Interaction
NLRP2 interacts wtih IKBKB, IKBKG, CHUK, and MEFV.
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction
Antigen References

1. Peng H, et al. 2012. PLoS One 7:e30344.
2. Lupfer C, et al. 2013. Front Immunol. 4:285.
3. Minkiewicz J, et al. 2013. Glia. 61:1113.
4. Huang JY, et al. 2013. Hum. Reprod. 28:1127.
5. Fontalba A, et al. 2007. J. Immunol. 179:8519.
6. Bruey JM, et al. 2004. J. Biol. Chem. 50:51897.

Gene ID
55655 View all products for this Gene ID
UniProt
View information about NLRP2 on UniProt.org

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