Purified anti-TdT Antibody
- 产品名称：
- Purified anti-TdT Antibody
- 产品类别：
- 抗体
- 产品编号：
- 659002
- 产品应用：
- 659002
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial human TdT recombinant protein (1-508aa) expressed in E. coli.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
The 7H9A33 clone has been shown to be useful for western blotting of human and mouse TdT.
- RRID
- AB_2562962 (BioLegend Cat. No. 659002)
- Structure
- 510 amino acids, predicted molecular weight of 58 kD.
- Distribution
-
Nucleus.
- Function
- Template-independent DNA polymerase catalyzing the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. It is also involved in the addition of nucleotides at the N region junction of rearranged immunoglobulin heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
- Interaction
- Interacts with PRP19 and DNTTIP1. Forms a ternary complex with DNTTIP2 and core histone.
- Cell Type
- B cells
- Biology Area
- Cell Biology, DNA Repair/Replication, Immunology
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
1. Yunk L, et al. 2009. J. Immunol. 183:452.
2. Kedzierska K, et al. 2008. J. Immunol. 181:2556.
3. Fuller SA, et al. 1985. Biochem. J. 231:105.
4. Feeney AJ, et al. 2001. J. Immunol. 167:3486.
5. Komori T, et al. 1993. Science 261:1171.
- Gene ID
- 1791 View all products for this Gene ID
- UniProt
- View information about TdT on UniProt.org
