Purified anti-DDX17 (p82, p72) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 323	1

规格

价格

库存

100µg

￥ 323

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial human DDX17 recombinant protein (1-107 a.a.)
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
ICC, IP - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 0.5 ?g per ml.?For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/ml is recommended. For immunoprecipitation, the suggested use of this reagent is 5.0 - 20 μg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: This antibody, clone 7G6B09, detects both human DDX17 isoform-1 (p82) and isoform-2 (p72) by Western blotting. Clone 1B5B09 detects only human DDX17 isoform-1 (p82) by Western blotting.
RRID: AB_2562551 (BioLegend Cat. No. 657302)

Structure: 729 amino acids, predicted molecular weight of 80 kD. Contains a helicase domain, an ATP-binding domain, and a transactivation domain.
Distribution: Nucleus
Function: DDX17 is a member of the DEAD box superfamily of RNA helicases, involved in RNA metabolism and transcriptional regulation.
Interaction: DDX17 interacts with DDX5, RNA polymerase II, CBP, p300, PCAF, NCOA1, NCOA2, NCOA3, ESR1, TP53, and HDAC1.
Biology Area: Cell Biology, Cell Cycle/DNA Replication, Signal Transduction, Transcription Factors
Molecular Family: Nuclear Markers
Antigen References: 1. Janknecht R. 2010. Am. J. Transl. Res. 2:223.
2. Wortham NC, et al. 2009. Oncogene. 28:4053.
3. Shin S, et al. 2007. Cancer Res. 67:7572.
4. Caretti G, et al. 2007. Cell Cycle 6:1172.
5. H?nig A, et al. 2002. Mol. Cell Biol. 22:5698.
6. Lamm GM, et al. 1996. Nucleic Acids Res. 24:3739.
Gene ID: 10521 View all products for this Gene ID
UniProt: View information about DDX17 on UniProt.org