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Purified anti-mouse CD204 Antibody
产品名称:
Purified anti-mouse CD204 Antibody
产品类别:
抗体
产品编号:
676202
产品应用:
676202
[价格]
规格 价格 库存
100µg ¥ 265 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Partial mouse CD204 recombinant protein (79-458 a.a.) expressed in 293E cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

CD204 is polymorphic and clone 7G5C33 may not react with all mouse strains. In house testing with this clone showed no reactivity to C57BL/6 mouse spleen samples.

The predicted molecular weight of CD204 is 50 kD, the observed molecular weight when clone 7G5C33 is used for western blot is ~70 kD. This is likely due to glycosylation of CD204 at multiple sites.

RRID
AB_2565623 (BioLegend Cat. No. 676202)

Antigen Details

Structure
485 amino acids with a predicted molecular weight of 50 kD and is a single-pass type II membrane protein.
Distribution

Plasma membrane, low-density lipoprotein particle, and endocytic vesicle emmbrane.

Function
CD204, a trimeric type II integral membrane glycoprotein, is predominantly expressed on macrophages and dendritic cells. CD204 plays important roles in lipid metabolism, host defense, and inflammatory responses.
Interaction
CD204 interacts with HSPA1A.
Biology Area
Cell Biology, Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Kelley JL, et al. 2014. Crit. Rev. Immunol. 34:241.
2. Saito Y, et al. 2014. J. Clin. Exp. Hematop. 54:59.
3. Jozefowski S, et al. 2014. Innate Immun. 20:826.
4. Haasken S, et al. 2013. J. Immunol. 191:1055.
5. Yu H, et al. 2012. Biochim. Biophys. Acta. 7:1192.
6. Yu X, et al. 2012. Oncoimmunology 5:770.

Gene ID
20288 View all products for this Gene ID
UniProt
View information about CD204 on UniProt.org

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