Direct-Blot™ HRP anti-IRF8 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µL	￥ 340	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial human IRF8 recombinant protein (116-220 a.a.)
Formulation: This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation: The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling: Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested dilution is 1:1000-1:4000. The optimal dilution should be determined by titration for each individual assay of interest.

25 ?l and 100 ?l of Direct-Blot? HRP antibody can be used for approximately 5 and 20 Western blots, respectively, at the recommended concentration/dilution.
RRID: AB_2617029 (BioLegend Cat. No. 656503)

Structure: 426 amino acids, predicted molecular weight of 48 kD, contains a IRF tryptophan pentad repeat responsible for DNA binding and a C-terminal IRF association domain (IAD) responsible for heterodimerization with other transcription factors
Distribution: Nucleus
Function: Transcription factor primarily expressed in hematopoietic cells, regulates expression of type I IFN and IFN-inducible genes in response to viral infection
Interaction: Interacts with BATF, JunB, TRIM21, and COPS2
Cell Type: B cells, Dendritic cells
Biology Area: Cell Biology, Immunology, Innate Immunity, Transcription Factors
Molecular Family: Nuclear Markers
Antigen References: 1. Minten C, et al. 2012. PLoS One. 7:e49851.
2. Xu H, et al. 2012. Nat. Immunol. 13:642.
3. Ouyang X, et al. 2011. Nat. Commun. 2:314.
4. Shin DM, et al. 2011. PLoS One. 6:e27384.
5. Wang H, et al. 2009. Immunol. Res. 43:109.
6. Qi CF, et al. 2009. Immunol. Res. 45:62.
Gene ID: 3394 View all products for this Gene ID
UniProt: View information about IRF8 on UniProt.org