Purified anti-NLRC4 (IPAF) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 265	1

规格

价格

库存

100µg

￥ 265

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial human NLRC4 recombinant protein (1-88 aa)
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
ICC?- Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2563347 (BioLegend Cat. No. 659702)

Structure: 1024 amino acids, predicted molecular weight of 116 kD. Contains a CARD domain, a NACHT domain, and 14 leucine-rich repeats.
Distribution: Cytoplasm.
Function: NLRC4 is involved in the assembly of the inflammasome complex, activation of pro-caspase-1, and induction of matured proinflammatory cytokines during bacterial infections.
Interaction: Foms homo-oligomer in NLRC4 inflammasome. Interacts with Caspase-1, ASC, NOD2, NALP1, and BCL10.
Cell Type: Dendritic cells
Biology Area: Cell Biology, Immunology, Innate Immunity, Signal Transduction
Antigen References: 1. Cai S, et al. 2012. J. Immunol. 188:5623.
2. Franchi L, et al. 2012. Nat. Immunol. 13:449.
3. Carvalho FA, et al. 2012. Mucosal Immunol. 5:288.
4. Tomalka J, et al. 2011. PLoS Pathog. 7:e1002379.
5. Pereira MS, et al. 2011. J. Immunol. 187:6447.
6. Sauer JD, et al. 2011. Proc. Natl. Acad. Sci. USA. 108:12419.
Gene ID: 58484 View all products for this Gene ID
UniProt: View information about NLRC4 on UniProt.org