首页 > 抗体蛋白 > 抗体
Purified anti-TOX Antibody
产品名称:
Purified anti-TOX Antibody
产品类别:
抗体
产品编号:
682601
产品应用:
682601
[价格]
规格 价格 库存
25µg ¥ 101 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human TOX recombinant protein (66-301 a.a.) expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 ?g per ml. For immunocytochemistry, a concentration range of 0.1 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The immunogen used to generate clone 6E6D03 is the N-terminus of Tox1, which is highly conserved among Tox family member proteins. Hence, this clone may recognize multiple Tox family members. Predicted MW for Tox family members: Tox 1 is 57.5 kD, Tox 2 is 49, 52, 53, 55 kD, Tox 3 is 63 kD and Tox 4 is 64, 66 kD.

Product Citations
  1. Sasawatari S, et al. 2020. J Immunol. 1373:204. PubMed
RRID
AB_2566642 (BioLegend Cat. No. 682601) AB_2566643 (BioLegend Cat. No. 682602)

Antigen Details

Structure
562 amino acids with a predicted molecular weight of 57.5 kD. Contains a high mobility group (HMG) box domain responsible for DNA binding.
Distribution

Nucleus.

Function
TOX is a transcription factor required for development of various T lymphocyte subsets.
Interaction
TOX interacts with ZDHHC17.
Biology Area
Cell Biology, Immunology, Innate Immunity, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Spits H. 2015. Nat. Immunol. 16:594.
2. Seehus CR, et al. 2015. Nat. Immunol. 16:599.
3. Huang Y, et al. 2015. Blood 125:1435.
4. Aliahmad P, et al. 2012. Curr. Opin. Immunol. 24:173.
6. Di Santo JP. 2010. Nat. Immunol. 11:885.
7. Aliahmad P, et al. 2004. J. Exp. Med. 199:1089.

Gene ID
9760 View all products for this Gene ID
UniProt
View information about TOX on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线