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Purified anti-IRF9 Antibody
产品名称:
Purified anti-IRF9 Antibody
产品类别:
抗体
产品编号:
660702
产品应用:
660702
[价格]
规格 价格 库存
100µg ¥ 288 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial human IRF9 recombinant protein (116-387 a.a.) expressed in E. coli.
Formulation
This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
Affinity purified.
Concentration
0.5 mg/mL
Storage & Handling
Upon receipt, store undiluted 2°C and 8°C.
Application

WB - Quality tested
ICC, ChIP - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.4 - 2.5 ?g per mL. For ChIP applications, the suggested dilution is 1:50 to 1:200 by volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This clone does not react with mouse (in-house tested). A non-specific band was observed (around 37 KD) when this antibody was tested on Raw264.7 cells

Product Citations
  1. Xiang Q, et al. 2022. PLoS Pathog. 18:e1010676. PubMed
RRID
AB_2563575 (BioLegend Cat. No. 660702)

Antigen Details

Structure
393 amino acids, predicted molecular weight of 44 kD; contains a IRF tryptophan pentad repeat responsible for DNA binding.
Distribution

Cytoplasm, phosphorylated form translocated to the nucleus.

Function
IRF9 is a transcription factor that mediates interferon signaling and activates the expression of interferon inducible genes.
Interaction
Forms the interferon-stimulated gene factor 3 complex (ISGF3) with Signal Transducer and Activator of Transcription 1 (STAT1) and STAT2 in response to type I IFN stimulation.
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Fink K and Grandvaux N, 2013. JAKSTAT. 2:e27521.
2. Tsuno T, et al. 2009. J. Immunother. 32:803.
3. Thibault DL, et al. 2008. J. Clin. Invest. 118:1417.
4. Kraus TA, et al. 2003. J. Biol. Chem. 278:13033.
5. Xiao W, et al. 2001. J. Biol. Chem. 276:23275.
6. Veals SA, et al. 1992. Mol. Cell. Biol. 12:3315.

Gene ID
10379 View all products for this Gene ID
UniProt
View information about IRF9 on UniProt.org

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