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Go-ChIP-Grade™ Purified anti-IRF9 Antibody
产品名称:
Go-ChIP-Grade™ Purified anti-IRF9 Antibody
产品类别:
抗体
产品编号:
660703
产品应用:
660703
[价格]
规格 价格 库存
25µg ¥ 83 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial human IRF9 recombinant protein (116-387 a.a.) expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ChIP -?Quality tested
WB, ICC -?Verified?

Recommended Usage

Each lot of this antibody is quality control tested by ChIP Assay. The suggested dilution for ChIP application is 1-50 to 1-200 by volume. For Western blotting, the suggested use of this reagent is 0.4 - 2.5 ?g per mL. It is recommended that the reagent to be titrated for optimal performance before each experiment.

Application Notes

This clone does not react with mouse (in-house tested). A non-specific band was observed (around 37 KD) when this antibody was tested on Raw264.7 cells

RRID
AB_2721591 (BioLegend Cat. No. 660703) AB_2721592 (BioLegend Cat. No. 660704)

Antigen Details

Structure
393 amino acids, predicted molecular weight of 44 kD; contains a IRF tryptophan pentad repeat responsible for DNA binding.
Distribution

Cytoplasm, phosphorylated form translocated to the nucleus.

Function
IRF9 is a transcription factor that mediates interferon signaling and activates the expression of interferon inducible genes.
Interaction
Forms the interferon-stimulated gene factor 3 complex (ISGF3) with Signal Transducer and Activator of Transcription 1 (STAT1) and STAT2 in response to type I IFN stimulation.
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Fink K and Grandvaux N, 2013.?JAKSTAT.?2:e27521.?
2. Tsuno T,?et al.?2009.?J. Immunother.?32:803.?
3. Thibault DL,?et al.?2008.?J. Clin. Invest.?118:1417.?
4. Kraus TA,?et al.?2003.?J. Biol. Chem.?278:13033.?
5. Xiao W,?et al.?2001.?J. Biol. Chem.?276:23275.?
6. Veals SA,?et al.?1992.?Mol. Cell. Biol.?12:3315.

Gene ID
10379 View all products for this Gene ID
UniProt
View information about IRF9 on UniProt.org

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