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Purified anti-TAL1 Antibody
产品名称:
Purified anti-TAL1 Antibody
产品类别:
抗体
产品编号:
681001
产品应用:
681001
[价格]
规格 价格 库存
25µg ¥ 112 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial human TAL1 recombinant protein (1-263 a.a.) expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. For immunocytochemistry, a concentration range of 1.0 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2566441 (BioLegend Cat. No. 681001) AB_2566442 (BioLegend Cat. No. 681002)

Antigen Details

Structure
331 amino acids with a predicted molecular weight of 34.3 kD. Contains a helix-loop-helix (bHLH) domain that is responsible for DNA binding and protein to protein interaction.
Distribution

Nucleus.

Function
TAL1 is a bHLH transcription factor that regulates hematopoietic and vascular development. Ectopic expression of TAL1 is linked to T-cell acute lymhoblastic leukemia (T-ALL).
Interaction
Forms heterodimers with TCF3. Interacts with ETS1, LMO2, and DRG1.
Biology Area
Cell Biology, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Wu W, et al. 2014. Genome Res. 24:1945.
2. Kolodziej S, et al. 2014. Nat. Commun. 5:3995.
3. Palii CG, et al. 2014. Cell Stem Cell 14:644.
4. Yun WJ, et al. 2014. Nucleic Acids Res. 42:4283.
5. Zhou Y, et al. 2013. Blood 26:4199.
6. Sanda T, et al. 2012. Cancer Cell 22:209.

Gene ID
6886 View all products for this Gene ID
UniProt
View information about TAL1 on UniProt.org

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