Ultra-LEAF™ Purified anti-human CD120b Antib-上海雅吉生物科技有限公司

规格	价格	库存
500µg	￥ 385	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Partial CD120b recombinant protein expressed in 293E cells (22-211aa).

Formulation

0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.

Preparation

The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

Concentration

The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.

Application

FC, Neut - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by neutralization. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations

Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
Ye LL, et al. 2020. Annals of Translational Medicine. 8(24):1647. PubMed

RRID

AB_2563224 (BioLegend Cat. No. 358408)

Antigen Details

Structure: 75 kD, type I transmembrane protein, member of the TNF-receptor superfamily, forms a heterocomplex with TNFRI
Distribution: Expressed on cells of hematopoietic lineage including monocytes, lymphocytes, and granulocytes
Function: When complexed with TNFRI, recruits anti-apoptotic molecules c-IAP1 and c-IAP2 that possess ubiquitin ligase activity; cysteine rich extracellular region
Interaction: Interacts with TTRAP and TRAF2
Ligand/Receptor: TNF-α and TNF-β (LT-α)
Cell Type: Granulocytes, Lymphocytes, Monocytes
Biology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience, Transcription Factors
Molecular Family: CD Molecules
Antigen References: 1. Andrews JS, et al. 1990. J. Immunol. 144:2582.
2. Nophar Y, et al. 1990. EMBO J. 9:3269.
3. Kohno T, et al. 1990. Proc. Natl. Acad. Sci. USA 87:8331.
4. Tartaglia LA, et al. 1991. Proc. Natl. Acad. Sci. USA 88:9292.
5. Hijdra D, et al. 2012. J. Inflamm. (Lond). 9:38.
6. Chen X, et al. 2013. J. Immunol. 190:1076.
Gene ID: 7133 View all products for this Gene ID
UniProt: View information about CD120b on UniProt.org

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