APC anti-human CD120b Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 154	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Partial CD120b recombinant protein expressed in 293E cells (22-211aa).

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Red Laser (633 nm)

Product Citations

Boyle M, et al. 2015. PLoS Pathog. 11: 1005041. PubMed
Liu H, et al. 2020. J Crohns Colitis. 1619:14. PubMed
Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
Beyer M, et al. 2016. Nat Immunol. 17:593-603. PubMed

RRID

AB_2562347 (BioLegend Cat. No. 358405) AB_2562348 (BioLegend Cat. No. 358406)

Antigen Details

Structure: 75 kD, type I transmembrane protein, member of the TNF-receptor superfamily, forms a heterocomplex with TNFRI
Distribution: Expressed on cells of hematopoietic lineage including monocytes, lymphocytes, and granulocytes
Function: When complexed with TNFRI, recruits anti-apoptotic molecules c-IAP1 and c-IAP2 that possess ubiquitin ligase activity; cysteine rich extracellular region
Interaction: Interacts with TTRAP and TRAF2
Ligand/Receptor: TNF-α and TNF-β (LT-α)
Cell Type: Granulocytes, Lymphocytes, Monocytes
Biology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience, Transcription Factors
Molecular Family: CD Molecules
Antigen References: 1. Andrews JS, et al. 1990. J. Immunol. 144:2582.
2. Nophar Y, et al. 1990. EMBO J. 9:3269.
3. Kohno T, et al. 1990. Proc. Natl. Acad. Sci. USA 87:8331.
4. Tartaglia LA, et al. 1991. Proc. Natl. Acad. Sci. USA 88:9292.
5. Hijdra D, et al. 2012. J. Inflamm. (Lond). 9:38.
6. Chen X, et al. 2013. J. Immunol. 190:1076.
Gene ID: 7133 View all products for this Gene ID
UniProt: View information about CD120b on UniProt.org

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