Purified anti-RAG2 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 288	1

规格

价格

库存

100µg

￥ 288

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial RAG2 recombinant protein (70-516 aa).
Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.05% sodium azide.
Preparation: Affinity purified.
Concentration: 0.5 mg/ml
Storage & Handling: Upon receipt, store undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5-2.5 ?g/ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application
RRID: AB_2561891 (BioLegend Cat. No. 654902)

Structure: 527 amino acids, predicted molecular weight of 59 kD. Containing a core RAG domain with DNA cleavage activity and an atypical PHD domain responsible for binding of trimethylated histone H3 (H3K4me3) and phospholipids.
Distribution: Nucleus.
Function: RAG2 protein acts as a core subunit of the RAG complex, which is responsible for V(D)J recombination of T-cell receptors and immunoglobulins.
Interaction: Interacts with RAG1, HMG1, and HMG2 in V(D)J recombination protein-DNA complexes.
Cell Type: B cells, Tregs
Biology Area: Cell Biology, Chromatin Remodeling/Epigenetics, Immunology, Neuroscience
Molecular Family: TCRs
Antigen References: 1. Fugmann SD, et al. 2000. Annu. Rev. Immunol. 18:495.
2. Oettinger MA. 1992. Trends Genet. 8:413.
3. Hillion S, et al. 2009. Autoimmun. Rev. 8:599.
4. Deriano L, et al. 2011. Nature 471:119.
5. van Til NP, et al. 2012. Mol Ther. 20:1968.
6. Jones JM and Simkus C, et al. 2009. Arch. Immunol. Ther. Exp. 57:105.
Gene ID: 5897 View all products for this Gene ID
UniProt: View information about RAG2 on UniProt.org