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Purified anti-NLRP12 Antibody
产品名称:
Purified anti-NLRP12 Antibody
产品类别:
抗体
产品编号:
675202
产品应用:
675202
[价格]
规格 价格 库存
100µg ¥ 311 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial human NLRP12 recombinant protein (93-1061 a.a.) expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2565493 (BioLegend Cat. No. 675202)

Antigen Details

Structure
1061 amino acids with a predicted molecular weight of 120 kD. Contains a DAPIN domain, a NACHT-associated domain, and eight leucine-rich repeats (LRR).
Distribution
Cytoplasm.
Function
NLRP12 negatively regulatres inflammation through attenuating both canonical and non-canonical NF-κB signaling.
Interaction
Interacts with ASC and FAF1 through its DAPIN domain.
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction
Antigen References

1. Allen IC. 2014. Front Immunol. 5:169.
2. Zaki MH, et al. 2014. Proc. Natl. Acad. Sci. USA 111:385.
3. Chen GY. 2014. Eur. J. Immunol. 44:321.
4. Vladimer GI. 2013. Curr. Opin. Microbiol. 16:23.
5. Allen IC, et al. 2012. Immunity 36:742.
6. Vladimer GI, et al. 2012. Immunity 37:96.

Gene ID
91662 View all products for this Gene ID
UniProt
View information about NLRP12 on UniProt.org

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