Alexa Fluor® 488 anti-Oct4 (Oct3) Antibody
- 产品名称：
- Alexa Fluor® 488 anti-Oct4 (Oct3) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 653705
- 产品应用：
- 653705
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial human Oct4 recombinant protein (1-141aa).
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Blue Laser (488 nm)
- Product Citations
-
- Ababneh NA, et al. 2020. Stem Cell Research. 49:102000. PubMed
- Wang W, et al. 2021. Front Pharmacol. 12:707940. PubMed
- Kuang YL, et al. 2019. Stem Cell Res. 37:101434. PubMed
- Ababneh NA, et al. 2020. Stem Cell Research. 47:101906. PubMed
- Ababneh NA, et al. 2021. Stem Cell Research. 54:102358. PubMed
- Ababneh NA, et al. 2020. Stem Cell Research. 48:101925. PubMed
- Ababneh NA, et al. 2020. Stem Cell Research. 47:101891. PubMed
- Petters J, et al. 2020. Stem Cell Research. 72.42222222. PubMed
- Ababneh NA, et al. 2020. Stem Cell Research. 48:101967. PubMed
- V ?lkner C, et al. 2020. Stem Cell Research. 41:101606.. PubMed
- Guzzardo P, et al. 2017. Sci Rep.. 10.1038/s41598-017-16931-z. PubMed
- RRID
- AB_2562250 (BioLegend Cat. No. 653705) AB_2562251 (BioLegend Cat. No. 653706)
- Structure
- Belongs to the POU transcription factor family, predicted molecular weight of 39 kD
- Distribution
-
Nuclear protein, expressed in undifferentiated embryonal carcinoma (EC) cells, embryonic stem (ES) cells and embryonic germ (EG) cells
- Function
- Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Oct4 is a prime candidate for an early developmental control gene. It also is an important marker of the undifferentiated state and central regulator of pluripotency in ES cells.
- Interaction
- SOX2, SOX8, SOX10, androgen receptor, and ETS2
- Biology Area
- Cell Biology, Immunology, Stem Cells, Transcription Factors
- Antigen References
-
1. Niwa H, et al. 2000. Nature Genet. 24:372.
2. Wernig M, et al. 2007. Nature 448:318.
3. Pesce M, et al. 2001. Stem Cells 19:271.
- Gene ID
- 5460 View all products for this Gene ID
- UniProt
- View information about Oct4 on UniProt.org
