PE/Cyanine7 anti-human IL-22 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 159	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Full length recombinant protein expressed in E. Coli.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Additional Product Notes

BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.

Product Citations

Khanam A, et al. 2021. Front Immunol. 11:599648. PubMed
Dupraz L, et al. 2021. Cell Reports. 36(1):109332. PubMed
Perveen K, et al. 2021. Int J Mol Sci. 0.916666666666667. PubMed

RRID

AB_2571930 (BioLegend Cat. No. 366707) AB_2571931 (BioLegend Cat. No. 366708)

Antigen Details

Structure: Cytokine.
Distribution: Thymic lymphomas, T cells, activated T cells, macrophages, mast cells, and Th17.
Function: Enhances the production of acute phase proteins in HepG2 cells and promotes Th17 cells to trasmigrate through the blood-brain barrier in multiple sclerosis.
Interaction: IL-22 receptor.
Ligand/Receptor: IL-22R1 and IL-10R2 receptor chains.
Cell Type: T cells, Macrophages, Th17, Mast cells, Embryonic Stem Cells
Biology Area: Immunology, Stem Cells
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Nagalakshmi ML, et al. 2004. Int. Immunopharmacol. 5:679.
2. Kebir H,, et al. 2007. Nat. Med. 13:1173.
3. Gu Y, et al. 2008. Eur. J. Immunol. 38:1807.
4. Pene Y, et al. 2008. J. Immunol. 180:7423.
5. Dumotier L, et al. 2000. J. Immune 164:1814.
6. Xie MH, et al. 2000. J. Biol. Chem. 40:31335.
7. Kotenko SV, et al. 2001. J. Immunol. 166:7096.
8. Chung Y, et al. 2006. Cell Res. 11:902.
9. Trifari S, et al. 2009. Nat. Immunol. 10:864.
Gene ID: 50616 View all products for this Gene ID
UniProt: View information about IL-22 on UniProt.org

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