Purified anti-FOXO1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 241	1

规格

价格

库存

100µg

￥ 241

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial human FOXO1 recombinant protein (544-655aa)
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
ICC, IP, IHC-P - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml.?For immunocytochemistry, a concentration of 5.0 μg/ml is recommended. For immunoprecipitation, the suggested use of this reagent is 5.0 - 20 μg per ml. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 8.0 - 10. ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2562793 (BioLegend Cat. No. 658102)

Structure: 655 amino acids, predicted molecular weight of 70 kD. Contains a C-terminal trans-activating domain and a Fork-head domain responsible for DNA binding.
Distribution: Cytoplasm, Nucleus
Function: FOXO1 is a transcription factor mediating Insulin signaling. It regulates expression of the genes involved in cell growth, differentiation, and metabolism.
Interaction: FOXO1 interacts with RUNX2, NLK, SIRT1, PRMT1, SKP2, ATF4, and p300.
Cell Type: B cells, Tregs
Biology Area: Cell Biology, Cell Cycle/DNA Replication, Immunology, Transcription Factors
Molecular Family: Nuclear Markers
Antigen References: 1. Trinh DL, et al. 2013. Blood. 121:3666.
2. Ouyang W, et al. 2012. Nature. 491:554.?
3. Ferdous A, et al. 2012. Transcription. 3:221.
4. Cifarelli V, et al. 2012. Mol. Endocrinol. 26:1213.
5. Kamagate A, et al. 2008. Cell Cycle. 7:3162.
6. Kousteni S. 2012. Bone. 50:437.
Gene ID: 2308 View all products for this Gene ID
UniProt: View information about FOXO1 on UniProt.org