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Alexa Fluor® 594 anti-Nur77 Antibody
产品名称:
Alexa Fluor® 594 anti-Nur77 Antibody
产品类别:
抗体
产品编号:
653504
产品应用:
653504
[价格]
规格 价格 库存
100µg ¥ 347 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial human Nur77 recombinant protein (1-266 aa)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICC?- Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration range of 1.0?- 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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RRID
AB_2563321 (BioLegend Cat. No. 653504)

Antigen Details

Structure
64 kD protein containing a DNA-binding domain, two zinc finger domain, and a potential ligand-binding domain
Distribution

Nucleus

Function
Nur77 is a transcription factor that mediates various physiological stimuli, such as growth factors, hormones, inflammatory, and energy metabolic signals. Nur77 plays roles in many important biological processes including cell growth, differentiation, and apoptosis.
Interaction
Interacts with GADD45GIP1 and Bcl-2.
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Transcription Factors
Molecular Family
Nuclear Markers, Steroid Receptors/Nuclear Receptors
Antigen References

1. Nakai A, et al. 1990. Mol. Endocrinol. 4:1438.
2. Han YH, et al. 2006. Oncogene 25:2974.
3. Li M, et al. 2010. Mol. Cell. Endocrinol. 319:39.
4. Pearen MA, et al. 2010. Mol. Endocrinol. 24:1891.
5. Moll UM, et al. 2006. Oncogene 25:4725.
6. Fassett MS, et al. 2012. Proc. Natl. Acad. Sci. USA 109:3891.

Gene ID
3164 View all products for this Gene ID
UniProt
View information about Nur77 on UniProt.org

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