Purified anti-NR5A2 Antibody
- 产品名称：
- Purified anti-NR5A2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 681202
- 产品应用：
- 681202
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial human NR5A2 recombinant protein (1-200 a.a.) expressed in E. coli.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 2.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2566455 (BioLegend Cat. No. 681202)
- Structure
- Orphan nuclear receptor, member of the FTZ-F1 sub-family, contains a DNA binding domain, 2 zinc finger motifs, a FTZ-F1 box, and a ligand-binding domain. Approximately 54 kD, three alternatively spliced variants exist.
- Distribution
- Nuclear, highly expressed in the pancreas, lower expression in the liver, and very low expression in the heart and lungs.
- Function
- Binds DNA as a monomer to regulate the transcription of the liver enzyme cholesterol 7-alpha-hydroxylase, which converts cholesterol to bile acids. Activates viral hepatitis B enhancer II to regulate liver-specific expression of this virus in combination with other transcription factors.
- Interaction
- Interacts wtih GRIP1, NCOA2, and NR0B2.
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Li M, et al. 1998. J. Biol. Chem. 273:29022.
2. Nitta M, et al. 1999. Proc. Natl. Acad. Sci. USA 96:6660.
3. Lee YK, et al. 2002. J. Biol. Chem. 277:2463.
4. Zhang CK, et al. 2001. Gene 273:239.
- Gene ID
- 2494 View all products for this Gene ID
- UniProt
- View information about NR5A2 on UniProt.org
