APC anti-human IL-31 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 142	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Full length human IL-31 recombinant protein expressed in E. coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: ICFC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
Excitation Laser: Red Laser (633 nm)
RRID: AB_2566762 (BioLegend Cat. No. 659605) AB_2566763 (BioLegend Cat. No. 659606)

Structure: 161 aa with with a putative 23 aa signal peptide that is cleaved to generate a 138 aa mature protein.
Distribution: Secreted by activated CD4 T cells.
Function: IL-31 belongs to the IL-6 family of cytokines and plays a role in skin inflammation.
Ligand/Receptor: Binds to IL-31 receptor complex that consists of two receptor subunits, IL31RA and OSMR.
Cell Type: T cells, Eosinophils
Biology Area: Cell Biology, Immunology
Molecular Family: Cytokines/Chemokines
Antigen References: 1. McCandless EE, et al. 2014. Vet. Immunol. Immunopathol. 157:42.
2. Arai I, et al. 2013. Exp. Dermatol. 22:669.
3. Dai X, et al. 2013. PLoS One. 8:e67666.
4. Stott B, et al. 2013. J. Allergy Clin. Immunol. 132:446.
5. Hartmann K, et al. 2013. J. Allergy Clin. Immunol. 132:232.
6. Baron JM and Lüscher B. 2012. Acta. Derm. Venereol. 92:5.
Gene ID: 386653 View all products for this Gene ID
UniProt: View information about IL-31 on UniProt.org