Purified anti-STAT6 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 118	1

规格

价格

库存

25µg

￥ 118

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial human STAT6 recombinant protein (678-847 aa)
Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: Affinity purified.
Concentration: 0.5 mg/ml
Storage & Handling: Upon receipt, store undiluted between 2°C and 8°C.
Application: WB - Quality tested
ICC, IP, ChIP - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml.?For immunocytochemistry, a concentration of 5.0 μg/ml is recommended. For immunoprecipitation, the suggested use of this reagent is 5.0 - 20 μg per ml. For ChIP applications, the suggested use of this reagent is 1:50-1:100 by volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2562691 (BioLegend Cat. No. 657901) AB_2562691 (BioLegend Cat. No. 657902)

Structure: 847 amino acids, predicted molecular weight of 94 kD. Contains a SH2 domain responsible for phosphor-Tyrosine binding and dimerization. The C-terminal LXXLL motif is required for interaction with NCOA1.
Distribution: Cytoplasm. Translocates to the nucleus when phosphorylated.
Function: STAT6 is a transcription factor, mediating IL-4 and IL-13 signaling.
Interaction: STAT6 interacts with CBP/p300 and NCOA1. Forms a homodimer or a heterodimer with other STAT family members.
Cell Type: B cells
Biology Area: Cell Biology, Immunology, Signal Transduction, Transcription Factors
Molecular Family: Nuclear Markers
Antigen References: 1. Goenka S, et al. 2011. Immunol. Res. 50:87.
2. Wurster AL, et al. 2000. Oncogene. 19:2577.
3. Akira S. 1999. Stem Cells 17:138.
4. Zamorano J, et al. 2005. J. Immunol. 174:2843.
5. David M, et al. 2001. Oncogene. 20:6660.
6. Takeda K, et al. 1996. Nature 380:627.
Gene ID: 6778 View all products for this Gene ID 20852 View all products for this Gene ID
UniProt: View information about STAT6 on UniProt.org