Purified anti-Cathepsin D Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 265	1

规格

价格

库存

100µg

￥ 265

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial human cathepsin D recombinant protein (21-412 a.a.) expressed in 293E cells.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2565905 (BioLegend Cat. No. 678502)

Structure: The 402 amino acid recombinant protein has a predicted molecular mass of approximately 44 kD. Aspartic endoproteinase.
Distribution: Lysosome. Secreted. CTSD is found in most cells and tissues of mammals. It is very abundant in macrophages.
Function: Lysosomal protein turnover, apoptosis, cell proliferation, cell invasion, neurodegeneration, and immune responses. Upregulated by estradiol, insulin, insulin-like growth factor, EGF, and FGF basic.
Ligand/Receptor: Caspase-8, collagen, fibronectin, proteoglycans, and laminin.
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Neurodegeneration, Neuroscience, Neuroscience Cell Markers, Protein Trafficking and Clearance
Molecular Family: Enzymes and Regulators, Lysosomal Markers
Antigen References: 1. Vetvicka V, et al. 1994. Cancer Lett. 79:131.
2. Johansson AC, et al. 2003. Cell Death Differ. 10:1253.
3. Cavailles V, et al. 1988. Nucleic Acids Res. 16:1903.
4. Bidere N, et al. 2003. J. Biol. Chem. 278:31401.
5. Conus S, et al. 2012. J. Biol. Chem. 25:21142.
6. Koike M, et al. 2001. J. Neurosci. 21:7526.
7. Cullen V, et al. 2009. Mol. Brain 2:5.
8. Dian D, et al. 2014. Histol. Histopathol. 29:433.
Gene ID: 1509 View all products for this Gene ID
UniProt: View information about Cathepsin D on UniProt.org