Purified anti-C/EBPα Antibody
- 产品名称：
- Purified anti-C/EBPα Antibody
- 产品类别：
- 抗体
- 产品编号：
- 662102
- 产品应用：
- 662102
- Verified Reactivity
- Human
- Reported Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Synthetic peptide (AKQLALAGLFPYQPPPP) conjugated to KLH.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC?- Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 0.5 ?g per mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This product weakly reacts with Mouse.
- Product Citations
-
- Oliveros-Matus P, et al. 2020. Front Pharmacol. 11:303. PubMed
- Li Y, et al. 2018. Front Immunol. 32:415. PubMed
- RRID
- AB_2564224 (BioLegend Cat. No. 662102)
- Structure
- 358 amino acids with a predicted molecular weight of 38 kD; contains a bZIP domain responsible for DNA binding.
- Distribution
-
Nucleus
- Function
- C/EBPα is a bZIP transcription factor that regulates proliferation and differentiation of myeloid cells and adipocytes.
- Interaction
- C/EBPα forms heterodimers with C/EBPβ and γ; interacts with CDK2, CDK4, PRDM16, UBN1, and ZNF638.
- Cell Type
- Neutrophils
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication, Immunology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. De Obaldia ME, et al. 2013. Nat. Immunol. 14:1277.
2. Di Tullio A, et al. 2011. Proc. Natl. Acad. Sci. USA. 108:17016.
3. Fan HY, et al. 2011. Mol. Endocrinol. 25:253.
4. Cai DH, et al. 2008. Oncogene. 27:2772.
5. Khanna-Gupta A. 2008. Blood Cells Mol. Dis. 41:77.
6. Janardhan HP. 2008. Sci. Signal. 1:jc2.
- Gene ID
- 1050 View all products for this Gene ID
- UniProt
- View information about C/EBPalpha on UniProt.org
