Purified anti-human Ikaros Antibody
- 产品名称:
- Purified anti-human Ikaros Antibody
- 产品类别:
- 抗体
- 产品编号:
- 687102
- 产品应用:
- 687102
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human Ikaros peptide (431-477 aa) conjugated to KLH Freund's adjuvant.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ChIP - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per mL. The recommended starting antibody to chromatin ratio is 4 ?g of antibody and 5 ?g of chromatin per IP. Optimal antibody to chromatin ratio should be determined by the end user. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
There are eight splicing variants with predicted MW 58, 53, 48(2), 43, 41, 31, 24 KDa. This antibody might recognize some of the isoforms.
- RRID
- AB_2616940 (BioLegend Cat. No. 687102)
- Structure
- Zinc-finger DNA binding protein, homo/heterodimer, 57.5 kD
- Distribution
-
Fetal and adult hematopoietic cells.
- Function
- Regulates lymphocyte differentiation.
- Interaction
- DNA.
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Cell Biology, Chromatin Remodeling/Epigenetics, Immunology, Signal Transduction, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Wargnier A, et al. 1995. Proc. Natl. Acad. Sci. USA 92:6930.
2. Tonnelle C, et al. 2009. Mol. Immunol. 46:1736.
3. Wang H, et al. 2014. Pediatr. Blood Cancer 61:2230.
- Gene ID
- 10320 View all products for this Gene ID
- UniProt
- View information about Ikaros on UniProt.org