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Go-ChIP-Grade™ Purified anti-human Ikaros An
产品名称:
Go-ChIP-Grade™ Purified anti-human Ikaros An
产品类别:
抗体
产品编号:
687103
产品应用:
687103
[价格]
规格 价格 库存
25µg ¥ 1162 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human Ikaros peptide (431-477 aa) conjugated to KLH Freund's adjuvant.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ChIP -?Quality tested
WB -?Verified?

Recommended Usage

Each lot of this antibody is quality control tested by ChIP assay. The recommended starting antibody to chromatin ratio is 4 ?g of antibody and 5 ?g of chromatin per IP. Optimal antibody to chromatin ratio should be determined by the end user. For Western blotting, the suggested use of this reagent is?0.5 - 2.0??g per mL.?It is recommended that the reagent to be titrated for optimal performance before each experiment.

Application Notes

There are eight splicing variants with predicted MW 58, 53, 48(2), 43, 41, 31, 24 KDa. This antibody might recognize some of the isoforms.

RRID
AB_2721587 (BioLegend Cat. No. 687103)

Antigen Details

Structure
Zinc-finger DNA binding protein, homo/heterodimer, 57.5 kD
Distribution

Fetal and adult hematopoietic cells.

Function
Regulates lymphocyte differentiation.
Interaction
DNA.
Cell Type
B cells, Dendritic cells
Biology Area
Cell Biology, Chromatin Remodeling/Epigenetics, Immunology, Signal Transduction, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Wargnier A, et al. 1995. Proc. Natl. Acad. Sci. USA 92:6930.
2. Tonnelle C, et al. 2009. Mol. Immunol. 46:1736.
3. Wang H, et al. 2014. Pediatr. Blood Cancer 61:2230.

Gene ID
10320 View all products for this Gene ID
UniProt
View information about Ikaros on UniProt.org

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