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FITC anti-mouse Ki-67 Antibody
产品名称:
FITC anti-mouse Ki-67 Antibody
产品类别:
抗体
产品编号:
652409
产品应用:
652409
[价格]
规格 价格 库存
25µg ¥ 1904 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
E. coli expressed partial mouse Ki-67 recombinant protein, 1816-2163 aa.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by our Ki-67 staining protocol below. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Medina-Reyes EI, et al. 2015. Environ Res. 136:424. PubMed
  2. Guillaumond F, et al. 2015. PNAS. 112:2473. PubMed
  3. Sharma SK, et al. 2015. J Immunol. 194:5529. PubMed
  4. Rodero MP, et al. 2014. J. Invest. Dermatol. 7:1991-7. PubMed
Product Citations
  1. Hu XF, et al. 2021. Theranostics. 3796:11. PubMed
  2. Lawson H, et al. 2021. Stem Cell Reports. 16:2784. PubMed
  3. Bhattacharjee A, et al. 2021. Immunity. 54(8):1745-1757.e7. PubMed
  4. Iwasaki Y, et al. 2016. PLoS One. 11: 0158282. PubMed
  5. Liu X, et al. 2021. eLife. 0.416666666666667. PubMed
  6. Li K, et al. 2022. J Immunother Cancer. 10:. PubMed
  7. Li H, et al. 2021. Nat Commun. 12:2773. PubMed
  8. Niu S, et al. 2016. J Immunol. 197: 3293 - 3301. PubMed
  9. Bertino P, et al. 2019. Oncoimmunology. 8:1601482. PubMed
  10. Hu Q, et al. 2022. Diabetes. 71:394. PubMed
  11. Yang Z, et al. 2020. Sci Rep. 17757:10. PubMed
  12. Zhang T, et al. 2022. Oncogene. . PubMed
  13. Pardy RD, et al. 2021. Nat Commun. 12:4051. PubMed
  14. Zhang C, et al. 2020. Cell Rep. 32:108206. PubMed
  15. Chen G, et al. 2021. Sci Adv. 7:eabg5686. PubMed
  16. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  17. Cheng Y, et al. 2019. Cell Rep. 28:1703. PubMed
  18. Webb ER, et al. 2022. iScience. 25:104995. PubMed
  19. Han X, et al. 2020. Mol Cells. 43:793. PubMed
  20. Zhang W, et al. 2019. Mar Drugs. 0.845138889. PubMed
  21. Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed
  22. Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
  23. MaruYama T, et al. 2015. J Leukoc Biol. 98: 385-393. PubMed
  24. van der Poel CE, et al. 2019. Cell Rep. 29:2745. PubMed
  25. Miyauchi K, et al. 2021. Nat Commun. 12:3789. PubMed
  26. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  27. Delmas A, et al. 2016. PLoS One. 11: 0163305. PubMed
  28. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  29. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  30. Li X, et al. 2021. Front Cell Dev Biol. 9:647713. PubMed
RRID
AB_2562140 (BioLegend Cat. No. 652409) AB_2562141 (BioLegend Cat. No. 652410)

Antigen Details

Structure
325 kD protein containing a forkhead-associated domain (FHA) and 13 tandem repeats
Distribution

Nucleus and chromosome

Function
Required for cell cycle progression and proliferation
Interaction
Interacts with KIF15; binds to MKI67IP through FHA domain
Biology Area
Cell Biology, Cell Cycle/DNA Replication, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Starborg M, et al. 1996. J. Cell. Sci. 109:143.
2. Byeon IJ, et al. 2005. Nat. Struct. Mol. Biol. 12:987.
3. Yerushalmi R, et al. 2010. Lancet. Oncol. 11:174.
4. Beltrami AP, et al. 2001. N. Engl. J. Med. 344:1750.
5. Sachsenberg N, et al. 1998. J. Exp. Med. 187:1295.
6. Nagy Z, et al. 1997. Acta. Neuropathol. 93:294.

Gene ID
17345 View all products for this Gene ID
UniProt
View information about Ki-67 on UniProt.org

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