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Brilliant Violet 421™ anti-mouse Ki-67 Antib
产品名称：
Brilliant Violet 421™ anti-mouse Ki-67 Antib
产品类别：
抗体
产品编号：
652411
产品应用：
652411
[价格]
规格 价格 库存
50µg ￥ 4004 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
E. coli expressed partial mouse Ki-67 recombinant protein, 1816-2163 aa.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by our Ki-67 staining protocol below.?For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application. Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.


Learn more about Brilliant Violet?.

This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Excitation Laser
Violet Laser (405 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Medina-Reyes EI, et al. 2015. Environ Res. 136:424. PubMed
  2. Guillaumond F, et al. 2015. PNAS. 112:2473. PubMed
  3. Sharma SK, et al. 2015. J Immunol. 194:5529. PubMed
  4. Rodero MP, et al. 2014. J. Invest. Dermatol. 7:1991-7. PubMed
Product Citations
  1. Piper CJM, et al. 2020. Cell Reports. 29(7):1878-1892.e7.. PubMed
  2. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  3. Nagai Y, et al. 2019. Front Immunol. 10:174. PubMed
  4. Montes de Oca R, et al. 2021. Mol Cancer Ther. 20:1941. PubMed
  5. Wang G, et al. 2021. Nat Commun. 12:5733. PubMed
  6. Yang W, et al. 2020. Mucosal Immunol. 13:788. PubMed
  7. Zhang H, et al. 2020. Cancer Cell. 37(1):37-54.e9.. PubMed
  8. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  9. Prasad M, et al. 2021. Front Immunol. 12:644483. PubMed
  10. Ma X, et al. 2021. Cell Metabolism. 33(5):1001-1012.e5. PubMed
  11. Ma X et al. 2019. Cell Metab. 30(1):143-156 . PubMed
  12. MacDonald A, et al. 2021. Front Immunol. 12:755995. PubMed
  13. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  14. Yao Y, et al. 2018. Cell. 175:1634. PubMed
  15. Koelwyn GJ, et al. 2020. Nat Med. 1452:26. PubMed
  16. Lehrke MJ, et al. 2021. Elife. 10:. PubMed
  17. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  18. Li N, et al. 2022. Nat Commun. 13:7281. PubMed
  19. Fedele C, et al. 2021. J Exp Med. 218: . PubMed
RRID
AB_2562663 (BioLegend Cat. No. 652411)

Antigen Details

Structure
325 kD protein containing a forkhead-associated domain (FHA) and 13 tandem repeats
Distribution

Nucleus and chromosome

Function
Required for cell cycle progression and proliferation
Interaction
Interacts with KIF15; binds to MKI67IP through FHA domain
Biology Area
Cell Biology, Cell Cycle/DNA Replication, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Starborg M, et al. 1996. J. Cell. Sci. 109:143.
2. Byeon IJ, et al. 2005. Nat. Struct. Mol. Biol. 12:987.
3. Yerushalmi R, et al. 2010. Lancet. Oncol. 11:174.
4. Beltrami AP, et al. 2001. N. Engl. J. Med. 344:1750.
5. Sachsenberg N, et al. 1998. J. Exp. Med. 187:1295.
6. Nagy Z, et al. 1997. Acta. Neuropathol. 93:294.

Gene ID
17345 View all products for this Gene ID
UniProt
View information about Ki-67 on UniProt.org

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