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首页 > 抗体蛋白 > 抗体
APC anti-mouse Ki-67 Antibody
产品名称：
APC anti-mouse Ki-67 Antibody
产品类别：
抗体
产品编号：
652405
产品应用：
652405
[价格]
规格 价格 库存
25µg ￥ 2086 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
E. coli expressed partial mouse Ki-67 recombinant protein, 1816-2163 aa.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by our Ki-67 staining protocol below. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Medina-Reyes EI, et al. 2015. Environ Res. 136:424. PubMed
  2. Guillaumond F, et al. 2015. PNAS. 112:2473. PubMed
  3. Sharma SK, et al. 2015. J Immunol. 194:5529. PubMed
  4. Rodero MP, et al. 2014. J. Invest. Dermatol. 7:1991-7. PubMed
Product Citations
  1. Bruand M, et al. 2021. Cell Reports. 36(3):109412. PubMed
  2. Bongiorno EK, et al. 2017. J Immunol. 198:4513. PubMed
  3. Efraim Y, et al. 2022. Cell Rep. 40:111307. PubMed
  4. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  5. Robinson BS, et al. 2020. Am J Pathol. 190:1657. PubMed
  6. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  7. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  8. Hsu J, et al. 2020. Proceedings of the National Academy of Sciences. 117(38):23626-23635. PubMed
  9. Wang W, et al. 2020. Cell Rep. 107936:32. PubMed
  10. Lino AC et al. 2018. Immunity. 49(1):120-133 . PubMed
  11. Ma X, et al. 2021. Cell Metabolism. 33(5):1001-1012.e5. PubMed
  12. Ma X et al. 2019. Cell Metab. 30(1):143-156 . PubMed
  13. Ping Y, et al. 2020. Front Cell Dev Biol. 0.890972222. PubMed
  14. Freitas JT, et al. 2021. Pigment Cell Melanoma Res. 34:1084. PubMed
  15. Supper E, et al. 2021. Nat Commun. 12:2482. PubMed
  16. Dietmar Herndler‐Brandstetter et al. 2018. Immunity. 48(4):716-729 . PubMed
  17. La T, et al. 2018. Cancer Res. 78:6666. PubMed
  18. Stotesbury C, et al. 2020. J Immunol. 204:1582. PubMed
  19. Emmerson E, et al. 2018. EMBO Mol Med. 10.15252/emmm.201708051. PubMed
  20. Bainor AJ et al. 2018. Cell reports. 25(10):2797-2807 . PubMed
  21. Wesely J, et al. 2017. Stem Cells Int. 2017:5762301. PubMed
  22. Hewitt KJ et al. 2017. Developmental cell. 42(3):213-225 . PubMed
  23. K?lin S et al. 2017. Cell metabolism. 26(3):475-492 . PubMed
  24. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  25. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  26. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  27. Xu L, et al. 2020. Nat Cell Biol. 1162:22. PubMed
  28. Hamaidi I, et al. 2020. Cell Metabolism. 32(3):420-436.e12. PubMed
  29. Li J, et al. 2021. Transl Oncol. 14:101116. PubMed
  30. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  31. J?r?s M, et al. 2014. J Exp Med. 211:605. PubMed
  32. Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
  33. Serr I, et al. 2016. Nat Commun. 7:10991. PubMed
  34. Jatho A, et al. 2022. Cells. 11:. PubMed
  35. Habener A, et al. 2021. J Allergy Clin Immunol. 147:2281. PubMed
  36. Chen S, et al. 2018. Nat Commun. 9:5298. PubMed
  37. Patterson DG, et al. 2021. J Immunol. 207:1798. PubMed
  38. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
RRID
AB_2561929 (BioLegend Cat. No. 652405) AB_2561930 (BioLegend Cat. No. 652406)

Antigen Details

Structure
325 kD protein containing a forkhead-associated domain (FHA) and 13 tandem repeats
Distribution

Nucleus and chromosome

Function
Required for cell cycle progression and proliferation
Interaction
Interacts with KIF15; binds to MKI67IP through FHA domain
Biology Area
Cell Biology, Cell Cycle/DNA Replication, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Starborg M, et al. 1996. J. Cell. Sci. 109:143.
2. Byeon IJ, et al. 2005. Nat. Struct. Mol. Biol. 12:987.
3. Yerushalmi R, et al. 2010. Lancet. Oncol. 11:174.
4. Beltrami AP, et al. 2001. N. Engl. J. Med. 344:1750.
5. Sachsenberg N, et al. 1998. J. Exp. Med. 187:1295.
6. Nagy Z, et al. 1997. Acta. Neuropathol. 93:294.

Gene ID
17345 View all products for this Gene ID
UniProt
View information about Ki-67 on UniProt.org

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