Purified anti-LEF1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1414	1

规格

价格

库存

25µg

￥ 1414

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial human LEF1 recombinant protein (1-298 aa)
Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.05% sodium azide.
Concentration: 0.5 mg/ml
Storage & Handling: Upon receipt, store undiluted between 2°C and 8°C.
Application: WB - Quality tested
IP - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1-1.0??g per ml (1:5000 - 1:500).?For immunoprecipitation, the suggested use of this reagent is 5-20 μg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: LEF-1 is known to have 7 isoforms.
RRID: AB_2561614 (BioLegend Cat. No. 653101) AB_2561615 (BioLegend Cat. No. 653102)

Structure: 44 kD protein containing a DNA-binding domain (HMG box), an CTNNB1-binding region, and a Prolin-rich domain
Distribution: Nucleus
Function: LEF1 is a transcription factor mediating canonical Wnt signaling pathway. It has been shown to function in hair bud formation, cancer development, tumorigenesis, angiogenesis, and T-cell maturation.
Interaction: Interacts with ALX4, AML-1, beta-catenin (CTNNB1), EP300, MITF, PIAS4, SMAD2, and SMAD3
Biology Area: Angiogenesis, Cell Biology, Immunology, Signal Transduction, Transcription Factors
Molecular Family: TCRs, Nuclear Markers
Antigen References: 1. Mallory MJ, et al. 2011. Mol. Cell. Biol. 31:2184.
2. Waterman ML, et al. 1991. Genes Dev. 5:656.
3. Hovanes K, et al. 2001. Nat Genet. 28:53.
4. Bruhn L, et al. 1997. Genes Dev. 11:640.
5. Nguyen A, et al. 2005. Int. J. Oncol. 27:949.
6. Petropoulos K, et al. 2008. J. Exp. Med. 205:515.
Gene ID: 51176 View all products for this Gene ID
UniProt: View information about LEF1 on UniProt.org