Purified anti-Cathepsin A Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3710	1

规格

价格

库存

100µg

￥ 3710

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial Cathepsin A recombinant protein (29 - 480 a.a.) expressed in 293E cells.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2572060 (BioLegend Cat. No. 683902)

Structure: 480 amino acids with a predicted molecular weight of 54.5 kD. Processed active form of Cathepsin A contains a 32 kD chain and a 20 kD chain. These chains form a disulfide-linked heterodimer.
Distribution: Lysosome.
Function: Cathepsin A is a serine carboxypeptidase required for the activation and stabilization of β-galactosidase and neuraminidase in the lysosomal compartment. Defects in the gene can cause the lysosomal storage disorder galactosialidosis.
Interaction: Cathepsin A interacts with CTNNBIP1, GABARAP, ELN, and VAPA.
Biology Area: Cell Biology, Neurodegeneration, Neuroscience, Neuroscience Cell Markers, Protein Trafficking and Clearance
Molecular Family: Enzymes and Regulators, Lysosomal Markers
Antigen References: 1. Kolli N, et al. 2014. J. Biol. Chem. 189:11592.
2. Takiguchi K, et al. 2000. J. Hum. Genet. 45:200.
3. Hahn CN, et al. 1998. Proc. Natl. Acad. Sci. USA 95:14880.
4. van der Spoel A, et al. 1998. EMBO J. 17:1588.
5. Rudenko G, et al. 1998. Proc. Natl. Acad. Sci. USA 95:621.
6. Galjart NJ, et al. 1991. J. Biol. Chem. 266:14754.
Gene ID: 5476 View all products for this Gene ID
UniProt: View information about Cathepsin A on UniProt.org